Swiss Academy of Pharmaceutical Sciences (SAPhS)

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11/24/2017

  • Dr. Mahmud Yunis, Technical Director BIOGRUND GmbH: "The Role of Different Binary Binder Systems on Ibuprofen-Tablets by Dry Granulation (Roller Compaction)".
  • Info: Dry granulation (by roller compaction) as a continuous process becomes more important for the pharmaceutical and related industries. That is the reason why the interest of different materials and their processing is growing. One negative aspect of the roller compaction is the work hardening effect. The term work hardening effect refers to the effect that granules often show a reduced tensile strength compared to direct compression. With the correct dry binding agent, it is possible to improve the mechanical properties and lower the work hardening effect.